Faculty
Isgouhi Kaloshian
Professor of Nematology (Ph.D., 1989, University of California, Riverside
Office: 2107A Genomics
Phone: (951)827-3913
Fax: (951)827-4434
E-mail: isgouhi.kaloshian@ucr.edu
Areas of Expertise
Plant-insect and plant-nematode interactions
Research Interests
Understanding how aphids and nematodes successfully colonize and reproduce on their host plants is the long turn goal of my research program. To dissect these plant-pest interactions, we study potato aphid and root-knot nematode interactions with their tomato host. This crop provides a unique opportunity to study these interactions as it contains resistant and susceptible tomato lines to these pests. Moreover, resistance to both pests is mediated by the same disease resistance gene Mi-1 that encodes a nucleotide binding leucine-rich repeat protein. To understand the mechanism of Mi-1-mediated defense, we investigate gene expression changes in the aphid and the plant host during aphid feeding. We also investigate the Mi-1-mediated resistance signal transduction pathway to both pests. Moreover, we study aphid salivary proteins to identify effectors that are recognized by the plant host and those that interfere with the host cellular processes.
Selected Publications
Mantelin, S., H.-C. Peng, B. Li, H. S. Atamian, F. L.W. Takken, and I. Kaloshian. 2011. The receptor-like kinase SlSERK1 is required for Mi-1-mediated resistance to potato aphids in tomato. Plant J. 67:459-471.
Bhattarai, K. K., H. S. Atamian, I. Kaloshian*, and T. Eulgem*. 2010. WRKY72-type transcription factors contribute to basal immunity in tomato and Arabidopsis as well as gene-for-gene resistance mediated by the tomato R-gene Mi-1. Plant J 63:229-240 (* co-corresponding authors).
Gerardo, N.N., B. Altincicek, C. Anselme, H. Atamian, 22 additional authors, including I. Kaloshian. 2010. Immunity and other defenses in pea aphids, Acyrthosiphon pisum. Genome Biology 11:R21.
International Aphid Genomics Consortium (including I. Kaloshian). 2010. Genome sequence of the pea aphid Acyrthosiphon pisum. PLoS Biology. Vol. 8: e1000313.
Mantelin, S., K. K. Bhattarai, and I. Kaloshian. 2009. Ethylene contributes to potato aphid susceptibility in a compatible tomato host. New Phytol. 183:444-456.
Bhattarai, K. K., Q-G. Xie, S. Mantlein, U. Bishnoi, T. Girke, D. A. Navarre, and I. Kaloshian. 2008. Tomato susceptibility to root-knot nematodes requires an intact JA signaling pathway. Mol. Plant-Microbe Interact. 21:1205-1214.
Bhattarai, K. K., Q. Li, Y. Liu, S. P. Dinesh-Kumar, and I. Kaloshian. 2007. The Mi-1-mediated pest resistance requires Hsp90 and Sgt1. Plant Physiol. 144:312-323
Bhattarai, K., Q.-G. Xie, D. Pourshalimi,T. Younglove,and I. Kaloshian. 2007. LeCoi1-regulated JA-dependent signaling pathway is not required for the Mi-1-mediated potato aphid resistance. Mol. Plant-Microbe Interact. 20:276-282.
Jablonska, B., J. S. S. Ammiraju, K. Bhattarai, O. Martinez de Ilarduya, S. Mantelin, P. A. Roberts, and I. Kaloshian. 2007. The Mi-9 gene from Solanum arcanum conferring heat-stable resistance to root-knot nematodes is a homologue of Mi-1. Plant Physiol. 143: 1044-1054.
Li,Q., Q.-G. Xie, J. Smith-Becker, D. A. Navarre, and I. Kaloshian. 2006. Mi-1-mediated aphid resistance involves salicylic acid and mitogen-activated protein kinase signaling cascades. Mol. Plant-Microbe Interact. 19:655-664.
Kaloshian, I. and L. L. Walling. 2005. Hemipterans as Plant Pathogens. Annu. Rev. Phytopathol. 43:491-521.